Zepp JA, Morley MP, Loebel C, Kremp MM, Chaudhry FN, Basil MC, Leach JP, Liberti DC, Niethamer TK, Ying Y, Jayachandran S, Babu A, Zhou S, Frank DB, Burdick JA, Morrisey EE. Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus. Science. 2021 Mar 12:371:aebc3172. PMID: 33707239 Blog post


Chao CM, Bellusci S, Zepp JA. P16INK4a and the Alveolar Niche Take Center Stage in Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 Jul 15. PMID:32668168

Zepp JA, Alvira CM. Nanoparticle delivery of Angiogenic Gene Therapy: Save the Vessels, Save the Lung! Am J Respir Crit Care Med. 2020 Apr 27. PMID:32338996

Niethamer TK, Stabler CT, Leach JP, Zepp JA, Morley MP, Babu A, Zhou S, Morrisey EE. Defining the Role of Pulmonary Endothelial Cell Heterogeneity in the Response to Acute Lung Injury. Elife. 2020 Feb 24;9:e53072. PMID: 32091393


Liberti DC, Zepp JA, Bartoni CA, Liberti KH, Zhou S, Liu M, Morley MP, Morrisey EE. Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate. Dev Biol. 2019 Jun 23. PMID:31242446.

Zepp JA and Morrisey EE. Cellular crosstalk in the development and regeneration of the respiratory system. Nat Rev Mol Cell Biol. 2019 Jun 19. PMID:31217577.

Frank DB, Penkala IJ, Zepp JA, Sivakumar A, Linares-Saldana R, Zacharias WJ, Stolz KG, Pankin J, Lu M, Wang Q, Babu A, Li L, Zhou S, Morley MP, Jain R, Morrisey EE. Early lineage specification defines alveolar epithelial ontogeny in the murine lung. Proc Natl Acad Sci U S A. 2019 Feb 19. PMID:30782824

Bulek K, Chen X, Parron V, Sundaram A, Herjan T, Ouyang S, Liu C, Majors A, Zepp J, Gao J, Dongre A, Bodaszewska-Lubas M, Echard A, Aronica M, Carman J, Garantziotis S, Sheppard D, Li X. IL-17A Recruits Rab35 to IL-17R to Mediate PKCα-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility. J Immunol. 2019 Mar 1;202(5):1540-1548. PMID: 306833702.


Zacharias WJ, Frank DB, Zepp JA, Morley MP, Alkhaleel F, Kong J, Zhou S, Cantu E, Morrisey EE. 2018. Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. Nature. Feb 28. PMID:29489752.


Zepp JA, Frank DB, Zacharias WJ, Cavanaugh C, Morley MM, Morrisey EE. Distinct mesenchymal lineages and niches promote epithelial self-renewal and myofibrogenesis in the lung. Cell. Sep 7;170(6):1134-1148. PMID:28886382.


Frank DB, Peng T, Zepp JA, Snitow M, Vincent T, Penkala IJ, Herriges MJ, Morley MP, Zhou S, Lu MM, Morrisey EE. Emergence of a wave of Wnt signaling that regulates lung alveologenesis through controlling epithelial self-renewal and differentiation. Cell Reports. Nov 22;17(9):2312-2325. PMID:27880906.

More Publications from Dr. Zepp…

Adapted from Zepp JA and Morrisey, 2019.
Predicted Ligand:Receptor Interactions